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Targeting the MCP-GPX4/HMGB1 axis for effectively triggering immunogenic ferroptosis in pancreatic ductal adenocarcinoma
10.1093/ijnp/pyx094 55
Similarly, miR-139-5p transcriptionally suppresses SLC7A11 to induce ferroptosis and inhibits the proliferation, invasion, and metastasis of PDAC cells [64]
654 With benefits like high transformation efficiency, large library capacity, and biosafety, human yeast display allows measuring human protein activities in a simplified organismal environment
GSH is capable of scavenging ROS through Nrf2-mediated heme oxygenase-1 induction and enhancing M1-like macrophage polarization regulation, showing that GSH may be a useful strategy to increase the human defense system (Mittal et al., 2014
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